Efficient Mixed-Model Association (EMMA)
Power Simulation Package

EMMA Power Simulation Package is a R package which allows a user to perform a statistical power experiment via in silico mapping. Given a set of genotypes and related matrix between individuals (kinship matrix), this package can estimate the threshold by generating null phenotypes and compute the statistical power using the random phenotypes with a correlation structure derived from user-specified genetic background and snp effects. The full details are described in Fine Mapping in 94 Inbred Mouse Strains Using a High-Density Haplotype Resource.

The current implementation of EMMA Power Simulation Package is available in an R package. The documentation is included in the installation package. If you have any further question, please contact Eun Yong Kang. This is the joint work of Nick Furlotte, and Eskin E.

This web-site is based upon work supported by National Science Foundation grants 0513612, 0731455, and 0729049, and NIH grants K25-HL080079 and U01-DA024417. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation or NIH.